PCSS Guidance Topic: Pregnancy and Buprenorphine Treatment
نویسندگان
چکیده
Clinical Questions: 1. If a female patient of child-bearing age is requesting buprenorphine treatment, what should I do? (i.e. informed consent, birth control, etc) 2. If a patient is already on buprenorphine. Should I keep her on it during a pregnancy? 3. Does it matter whether she is given the mono (buprenorphine) or combo (buprenorphine/naloxone) product? 4. If a new opioid-dependent patient is pregnant and requests buprenorphine treatment, what should I do? 5. Is buprenorphine treatment during pregnancy safe? 6. How can detoxification (medically supervised withdrawal) be carried out if a pregnant patient wants to stop all opioids, including buprenorphine? 7. How does buprenorphine treatment compare with methadone treatment for pregnant women? 8. Does treatment of pregnant women change, depending on whether the patient abuses heroin or prescription opioids? 9. Is breastfeeding safe while taking buprenorphine? 10. What neonatal withdrawal is expected when mothers take buprenorphine?
منابع مشابه
PCSS-B Guidance Topic: Clinically Relevant Drug Interactions: Buprenorphine or Methadone with Other Frequently Prescribed Drugs
متن کامل
Buprenorphine and methadone treatment of opiate dependence during pregnancy: comparison of fetal growth and neonatal outcomes in two consecutive case series.
AIM To compare the effects of fetal buprenorphine and methadone exposure during maintenance treatment of pregnant heroin dependent subjects. DESIGN AND SETTING A population based comparison of consecutive, prospectively followed buprenorphine-exposed pregnancies in Stockholm County, Sweden, to retrospectively analyzed consecutive methadone-exposed pregnancies. PARTICIPANTS All 47 pregnancie...
متن کاملA Comparison of Buprenorphine + Naloxone to Buprenorphine and Methadone in the Treatment of Opioid Dependence during Pregnancy: Maternal and Neonatal Outcomes
Given that buprenorphine + naloxone is prescribed for opioid-dependent pregnant women, it is important to examine the extent to which it differs from buprenorphine alone, methadone, or methadone-assisted withdrawal on neonatal and maternal outcomes. Summary statistics on maternal and neonatal outcomes were collected from 7 previously published studies examining treatment for opioid-dependent pr...
متن کاملMethadone and buprenorphine for opioid dependence during pregnancy: a retrospective cohort study.
OBJECTIVES To compare maternal characteristics, prenatal care, and newborn outcomes in a cohort of opioid-dependent pregnant women treated with methadone versus buprenorphine. METHODS In a retrospective cohort study, 609 pregnant, opioid-dependent women were treated with methadone (n = 248) or buprenorphine (n = 361) between 2000 and 2012 at a single institution. RESULTS Mothers treated wit...
متن کاملNeonatal outcomes following in utero exposure to buprenorphine/naloxone or methadone
OBJECTIVES To study neonatal outcomes following buprenorphine/naloxone and methadone exposure during pregnancy. METHODS This study is a retrospective review of clinical and demographic information of 58 infants whose mothers were treated with buprenorphine/naloxone and 92 infants whose mothers were treated with methadone for opioid dependence during pregnancy. RESULTS Gestational age, birth...
متن کامل